Studies On Alterations Of Serum Proteins, Lipid Profile And Bilirubin Levels In Preeclamptic Women
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Studies On Alterations Of Serum Proteins, Lipid Profile And Bilirubin Levels In Preeclamptic Women
ABSTRACT
Pre-eclampsia is defined as having a systolic blood pressure (SBP) of 140mmHg or higher and a diastolic blood pressure (DBP) of 90mmHg or higher (Jameil et al., 2014). Pre-eclampsia is a condition that affects multiple organs and maternal systems, including the vascular system, liver, kidneys, and brain (Steegers et al., 2010).
It is a pregnancy issue that can cause problems for both the mother and the baby. Pre-eclampsia is also distinguished by the presence of protein in urine, known as proteinuria. The condition affects approximately 2-4% of pregnancies (Lana et al., 2004).
Despite extensive research in this area, the cause of pre-eclampsia is unknown. It is also known as the “disease of theories” and appears to have a complex origin. There are various signs and symptoms of pre-eclampsia.
Although these signs and symptoms are not usually specific to pre-eclampsia, they are similar to those of pregnancy, including swelling, pitting oedema, convulsions, and epigastric discomfort (Jameil et al., 2014).
Pre-eclampsia can be caused by a combination of genetic, immunological, and placental factors. Proteins are huge molecules composed of amino acids held together by peptide bonds (Chatterjea and Rana, 2012). All proteins contain carbon, hydrogen, oxygen, nitrogen, and sulphur. These are fundamental to their structure.
There are numerous protein sources, such as milk, eggs, and beans. There are numerous types of proteins. Examples of proteins include albumin, globulin, lipoproteins, and so on. Protein is commonly found in urine in pre-eclampsia.
Protein, a big molecule, is not expected to be detected in urine. However, because of damage to the kidney’s glomeruli in a pre-eclamptic patient, protein is generally present in urine.
As a result, protein levels are typically lower in pre-eclamptic patients. Serum albumin levels in a pre-eclamptic patient fall throughout the three trimesters due to hemodilution and increased demand from the developing foetus.
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