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Historical Changes On Plaintain Attenuated Indomethacin Induced Gastric Injury In Albino Wistar Rats

Historical Changes On Plaintain Attenuated Indomethacin Induced Gastric Injury In Albino Wistar Rats

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Historical Changes On Plaintain Attenuated Indomethacin Induced Gastric Injury In Albino Wistar Rats

INTRODUCTION

Food begins to be digested and absorbed in the stomach, though absorption is typically limited to water, alcohol, and some medicines. The stomach is an expanding, muscular pouch that retains swallowed food by contracting the muscular pyloric sphincter.

Food can remain in the stomach for two hours or more. Food is digested chemically by gastric juice and mechanically by the contraction of the three layers of smooth muscle in the muscular exterior layer.

Chyme is the broken-up food that results from this process. stomach juice is produced by stomach mucosal glands and contains hydrochloric acid, mucus, and the proteolytic enzymes pepsin (which breaks down proteins) and lipase (which breaks down fat).

It generally extends to hold approximately one litre of food. A newborn human baby’s stomach can only hold approximately 30 millilitres (Sherwood and Lauralee 2007). When the stomach is empty and not bloated, the lining rises into folds known as rugae.

After eating, these creases flatten, allowing the stomach to expand substantially. The stomach is divided into three anatomical regions: cardiac, which contains mucous secreting glands (called cardiac glands) and is closest to the oesophagus fundus; and body, which contains the gastric (fundic) glands pyloric, which secretes two types of mucus and the hormone gastrin (Brunicardi, Charles, and Dana, 2010).

 

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