Project Materials

THE EFFECT OF PTEROCARPUS MILDBREADII SEED ON PLASMA HDL CHOLESTEROL OF ALBINO RAT

ABSTRACT

This study was conducted to look into the effects of pterocarpus mildbreadii seed on the HDL levels of albino rats. High Density Lipoprotein (HDL) is a cholesterol component that aids in the transportation of cholesterol from the peripheral cells to the liver. High density lipoprotein is used to study cardiovascular illnesses. Fresh oha seed (pterocarpus mildbreadii seed) was obtained from Amokwe in the udi local government area of Enugu state. They were dried at room temperature for roughly a month in an open laboratory space, ground into coarse powder, and weighed with an electrical weighing balance. 3% tween-80 was made by dissolving it in 97mL of distilled water. The pulverised Pterocarpus mildbreadii was dissolved in 3% Tween-80. This analysis involved sixteen wistar abino rats. The rats were divided into four groups. Group 1 consisted of four rats and got 0.5 each of 3% tween-80. Group 2 consisted of five rats who were given a solution of Pteridocarpus mildreadii at a dosage of 1400 mg/kg body weight. Group 3 consisted of three rats who were given 2600mg/kg body weight of pteridocarpus mildbreadii solution. Group 4 consisted of four rats who were given Edmard MRT complex at a dose of 500mg/kg body weight.

Chapter one

INTRODUCTION

Pterocarpus mildbreadii are trees with edible parts that have successfully budded. Pterocarpus species (P. Soyauxii and P. mildbeadii) have different leaf flush patterns, one spontaneous and the other intermittent, making the first suitable for commercial production and the second for home production (Okafor 1978). Pterocarpus mildbreadii is the main case study for both vegetables and seeds.

The vegetable is often used in our varied households for cooking. Pterocarpus mildbreadii (Oha seed) is not consumed by the natives of eastern Nigeria.

As a result, the contents of this oha seed cannot be discussed in detail. The need for vegetable oils as a result of dwindling oil and fat sources necessitates the development of new sources as well as the exploitation of previously untapped sources to augment the existing ones (Minzangi et al. 2011).

Industrialists continue to rely heavily on popular vegetable oils such as coconut oil, soyabean oil, ground nut oil, and palm oil for the preparation and production of their diverse products.