Project Materials

THE EFFECT OF PTERROCARPUS MILDBREADII SEED ON PLASMA HLD CHOLESYEROL OF ALBINO RAT

ABSTRACT

The purpose of this study was to examine how pterocarpus mildbreadii seed affected the HDL-level in albino rats. A portion of cholesterol called high density lipoprotein (HDL) aids in the movement of cholesterol from the cell’s periphery to the liver. Cardiovascular disorders are investigated using high density lipoprotein. Fresh oha (Pterocarpus mildbreadii) seeds were gathered from Amokwe in the state of Enugu’s Udi local government area. They were ground into coarse form, dried for approximately a month at room temperature in an open laboratory area, and then weighed using an electrical weighing balance. To make 3% tween-80, 3% tween-80 was dissolved in 97 millilitres of distilled water. In 3% tween-80, the ground Pterocarpus mildbreadii was dissolved. For this investigation, sixteen Wistar Abino rats were employed. There were four (four) groups of rats. Four rats in Group 1 were given 0.5 of 3% tween-80 apiece. Pteridocarpus mildreadii solution (1400 mg/kg b.w.) was given to five rats in Group 2. Three rats in Group 3 received a pteridocarpus mildbreadii solution at a dose of 2600 mg/kg b.w. Four rats in Group 4 received 500 mg/kg b.w. of the Edmard MRT complex.

CHAPTER ONE

INTRODUCTION

According to reports, Pterocarpus species (P. Soyauxii and P. mildbeadii) have distinct patterns of leaf flush, one spontaneous and the other intermitted, making the former suitable for commercial production and the latter for home production. Pterocarpus mildbreadii are trees with edible parts that have successfully budded (Okafor 1978).

The primary case study for both the vegetable and the seeds is Pterocarpus mildbreadii. The vegetable is primarily utilised for cooking in our different homes. The eastern Nigerian population does not eat Pterocarpus mildbreadii (Oha seed). Therefore, the content of this oha seed cannot be largely stated.

Because the supply of oils and fats is running low, there is a need for vegetable oils, which leads to the need for both new and untapped sources to supplement the ones that are already available (Minzangi et al. 2011).

In order to prepare and produce their varied products, industrialists still mostly rely on popular vegetable oils such as coconut oil, soy oil, ground nut oil, palm oil, etc.

Additionally, plant lipids have nutritional importance and influence global economics and human nutrition. Seed and fruit triglycerol accounts for over three-quarters of the edible and industrial oils sold each year (Schimid & Ohlrogge, 2002). Because of their nutritional and calorific importance, seeds are essential to diets.

They are a good source of fats and edible oils. When completely digested, 1g of fat and oil provides more than twice as many joules of energy as protein and carbohydrates.

According to Odoemelan (2005), fat enhances the flavour of food, prolongs the feeling of fullness, and makes meals more fulfilling. Unfortunately, research into lesser-known, underutilised legumes and nutrient-dense oil seeds has become more necessary due to the scarcity of animal protein and the high cost of plant protein sources (Schimid & Ohlrogge, 2002).